Here you can find what I am working on:
I am mostly interested in understanding physical properties of biological systems at molecular scale. As a part of my Ph.D. thesis, I am investigating the underlying mechanism by which amyloid-beta protein interacts with silica surface. Our ultimate goal is to find out how this mechanism affects the aggregation of amyloid-beta protein which is the main issue in many neurodegenerative diseases such as Alzheimer. Nanoparticles have been extensively used for therapeutic reasons and this can be a good news if they can affect protein fibrillation process, possibly inhibiting or accelerating it depending on environmental conditions. Below you can see how hydrophobic core of amyloid beta comes immediately to the surface. This movie takes only 15 nanoseconds in simulation time scale.